Feline Infectious Peritonitis (FIP) is a viral disease with a 96% fatality rate. Once considered a death sentence for cats, effective treatments are now available to save infected cats.
BasmiFIP offers two main treatment options:
GS-441524 – the leading choice in FIP treatment, with a 93% success rate.
EIDD-1931 (MolnuFIP™) – a newer, more affordable antiviral that is 7.3x more potent than GS-441524.
This article compares their benefits, drawbacks, and dosages to help you choose the best solution for your beloved cat.
What Is GS-441524?
GS-441524 is a nucleoside analog that inhibits the replication of the coronavirus responsible for FIP. With a 93% success rate, this drug has saved thousands of cats worldwide and remains the preferred choice for many veterinarians.
Benefits of GS-441524:
Effective against all types of FIP (wet, dry, neurological, and ocular).
Safe for long-term use – 0% cytotoxicity (does not harm cells).
Available in injection and capsule form, offering flexible dosing options.
Provides treatment for up to 84 days without a high risk of mutagenicity.
Drawbacks of GS-441524:
Higher cost, making it inaccessible for some pet owners.
FIP virus may develop resistance, especially in neurological cases.
Daily injections can be challenging, especially for long-term treatment.
GS-441524 Dosage:
Wet FIP: 6 mg/kg every 24 hours
Dry FIP: 8 mg/kg every 24 hours
Neurological/Ocular FIP: 10 mg/kg every 24 hours
Treatment Duration: 12 weeks (84 days)
What Is EIDD-1931 (MolnuFIP™)?
EIDD-1931 is the active metabolite of Molnupiravir, specifically developed for FIP. Clinical studies show that EIDD-1931 is 7.3x more potent than GS-441524, with a 97% success rate.
Benefits of EIDD-1931 (MolnuFIP™):
More affordable – 1/10th the cost of GS-441524.
More potent – requires a lower dose for the same effect.
Capsule form – no need for injections, making administration easier.
No reported drug resistance so far.
Recovery starts within one week, with a 97% success rate.
Drawbacks of EIDD-1931 (MolnuFIP™):
2.8% cytotoxicity – mild effects on the liver and kidneys with prolonged use.
Short half-life – must be given every 12 hours to maintain effectiveness.
Not recommended for neurological or ocular FIP, due to limited penetration into the central nervous system.
Maximum treatment duration is 60 days – if FIP persists, switching to GS-441524 is necessary.
EIDD-1931 (MolnuFIP™) Dosage:
Wet/Dry FIP: 2.3 mg/kg every 12 hours
Ocular FIP: 3.5 mg/kg every 12 hours
Neurological FIP: Not recommended
Treatment Duration: Maximum 60 days
Why Must It Be Given Every 12 Hours?
The half-life of EIDD-1931 is only 1-1.3 hours, much shorter than GS-441524 (~4 hours). This means the drug must be administered more frequently to remain effective.
Which One Should You Choose?
Choose GS-441524 if:
You want a well-established treatment with the highest safety level.
You can afford a higher cost.
Your cat has neurological or ocular FIP, as EIDD-1931 is not recommended for these cases.
You want to avoid long-term cytotoxicity risks.
If your cat has kidney and liver issues.
If your cat has poor appetite, is vomiting or has diarrhoea.
Choose EIDD-1931 (MolnuFIP™) if:
You need a more affordable solution without sacrificing effectiveness.
Your cat has wet or dry FIP, but not neurological or ocular FIP.
You can administer the medication every 12 hours consistently.
Recommended Treatment Combinations:
Neurological/Ocular FIP: Start with GS-441524 injections for 30 days, then switch to GS-441524 capsules for the remaining 84 days.
Wet/Dry FIP without complications: Start with EIDD-1931 for 30 days If there are no liver and kidney problems., then assess the condition. If symptoms persist, continue EIDD-1931 up to 60 days. If FIP is still present, switch to GS-441524.
Conclusion: FIP Can Now Be Treated!
Both GS-441524 and EIDD-1931 (MolnuFIP™) offer effective solutions for treating FIP.
GS-441524 is ideal for those looking for the safest and most complete treatment, especially for neurological and ocular FIP.
EIDD-1931 (MolnuFIP™) provides a more affordable alternative with high effectiveness for wet and dry FIP.
If your cat is showing FIP in cats symptoms, please take them to your nearest veterinarian for proper diagnosis and treatment and if you have any questions or concerns about FIP and its treatment, please do not hesitate to reach out to us at Facebook or visit our Instagram to get in touch with our expert team.
You need a more affordable solution without sacrificing effectiveness.
Your cat has wet or dry FIP, but not neurological or ocular FIP.
You can administer the medication every 12 hours consistently.
Recommended Treatment Combinations:
Neurological/Ocular FIP: Start with GS-441524 injections for 30 days, then switch to GS-441524 capsules for the remaining 84 days.
Wet/Dry FIP without complications: Start with EIDD-1931 for 30 days If there are no liver and kidney problems., then assess the condition. If symptoms persist, continue EIDD-1931 up to 60 days. If FIP is still present, switch to GS-441524.
